CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-β3 function
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چکیده
منابع مشابه
Tankyrase 1 regulates centrosome function by controlling CPAP stability.
CPAP--a gene mutated in primary microcephaly--is required for procentriole formation. Here we show that CPAP degradation and function is controlled by the poly(ADP-ribose) polymerase tankyrase 1. CPAP is PARsylated by tankyrase 1 in vitro and in vivo. Overexpression of tankyrase 1 leads to CPAP proteasomal degradation, preventing centriole duplication, whereas depletion of tankyrase 1 stabilize...
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ژورنال
عنوان ژورنال: Bone
سال: 2016
ISSN: 8756-3282
DOI: 10.1016/j.bone.2015.11.007